Drug, substance that affects the function of living cells, used in medicine to diagnose, cure, prevent the occurrence of diseases and disorders, and prolong the life of patients with incurable conditions.
Since 1900 the availability of new and more effective drugs such as antibiotics, which fight bacterial infections, and vaccines, which prevent diseases caused by bacteria and viruses, has increased the average American’s life span from about 60 years to about 75 years. Drugs have vastly improved the quality of life. Today, drugs have contributed to the eradication of once widespread and sometimes fatal diseases such as poliomyelitis and smallpox.
CLASSIFICATION
Drugs can be classified in many ways: by the way they are dispensed——over the counter or by prescription; by the substance from which they are derived—plant, mineral, or animal; by the form they take—capsule, liquid, or gas; and by the way they are administered—by mouth, injection, inhalation, or direct application to the skin (absorption). Drugs are also classified by their names. All drugs have three names: a chemical name, which describes the exact structure of the drug; a generic or proprietary name, which is the official medical name assigned by the United States Adopted Name Council (a group composed of pharmacists and other scientists); and a brand or trade name given by the particular manufacturer that sells the drug. If a company holds the patent on a drug—that is, if the company has the exclusive right to make and sell a drug, then the drug is available under one brand name only. After the patent expires, typically after 17 years in the United States, other companies can also manufacture the drug and market it under the generic name, or give it a new brand name.
Another way to categorize drugs is by the way they act against diseases or disorders: chemotherapeutic drugs attack specific organisms that cause a disease without harming the host, while pharmocodynamic drugs alter the function of bodily systems by stimulating or depressing normal cell activity in a given system. The most common way to categorize a drug is by its effect on a particular area of the body or a particular condition.
World Health Organization
Human Disease
Human Disease, in medicine, any harmful change that interferes with the normal appearance, structure, or function of the body or any of its parts. Since time immemorial, disease has played a role in the history of societies. It has affected—and been affected by—economic conditions, wars, and natural disasters. Indeed, the impact of disease can be far greater than better-known calamities. An epidemic of influenza that swept the globe in 1918 killed between 20 million and 40 million people. Within a few months, more than 500,000 Americans died—more than were killed during World War I (1914-1918), World War II (1939-1945), the Korean War (1950-1953), and the Vietnam War (1959-1975) combined.
Diseases have diverse causes, which can be classified into two broad groups: infectious and noninfectious. Infectious diseases can spread from...